Regenerative full-thickness, functional skin.

Skin is more than just layered cell, growth factors and scaffolds—the combination that many current therapies are modeled from. It is more than a single layer to provide a barrier—it is the largest organ in the human body with numerous functions that require regeneration of all components and layers.

SkinTE is a first-of-its-kind entirely autologous, homologous product intended for skin repair, reconstruction, replacement, and supplementation. SkinTE treatment has resulted in regenerative full-thickness healing of skin with all its layers (epidermis, dermis and hypodermis) and its appendages.

What are the Intended Uses of SkinTE?

SkinTE can be used by physicians and other medical providers to repair, reconstruct, replace or supplement a patient's damaged or missing skin tissue.

How is SkinTE used?

Medical providers take a small, full-thickness skin sample from the patient (autologous) and returns it to PolarityTE in the provided parcel.

PolarityTE manufactures SkinTE.

SkinTE is contained within a syringe and is returned to provider in all-inclusive Deployment Box as soon as same day, and typically within 48-72 hours based on providers’ requests.

Provider applies SkinTE to patient’s wound/defect, covers with dressings and cares for wound/defect similar to standard of care for skin grafts.

Medical providers have used SkinTE for the treatment of:

  • Wounds (acute & chronic)
  • Surgical reconstruction events
  • Burns (acute, subacute & burn reconstruction)
  • Scar revision
  • Traumatic injuries
  • Replacement of skin grafts or failed flap coverage

Case Studies

SkinTE is a versatile product that can be used to treat any functional loss or void of skin. Learn more about clinical outcomes and how SkinTE has been used to treat specific types of wounds and skin defects.

Contact our Clinical Science Managers at for current case studies, and visit our Scientific Communications page for links to published data on SkinTE. Case studies are solely for the purposes of evaluating SkinTE for professional clinical use.

SkinTE Support Documents

SkinTE was designed and developed to be simple for providers to use. Learn more about how to use SkinTE.

Reimbursement Information

PolarityTE offers appropriate education for professionals to understand the coding options for the application of SkinTE, for both the harvest and deployment phases. The SkinTE Reimbursement Guide can be a useful resource. For additional information about coding and reimbursement of SkinTE, please contact the PolarityTE Reimbursement Team at 1-800-284-0262, or email

Access to the product sparking a paradigm shift

SkinTE is available for patients who have functional loss or void of skin/integument systems.

Contact PolarityTE for more information about clinical use of SkinTE: or 1-833-631-9954

For more information about reimbursement for SkinTE contact: or 1-800-284-0262

To order SkinTE contact:

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About SkinTE™

SkinTE is a human cellular and tissue-based product derived from a patient’s own skin (autologous) intended for the repair, reconstruction, replacement or supplementation (i.e., homologous use) of skin tissue and the integumentary system. Aseptic surgical procedures and handling during skin harvest, wound preparation and SkinTE deployment are mandatory.

Important Safety Information

SkinTE is donated human tissue for autologous, single application use only. SkinTE has not been evaluated for infectious substances. SkinTE may contain trace amounts of antibiotics (e.g., gentamicin), which may potentially cause an adverse effect in patients who are hypersensitive or allergic to antibiotics. For patients sensitive to or allergic to gentamicin, alternative processing is available with prior notice. Patients with multiple comorbidities, or who have any condition that could compromise recipient site vascularity and wound healing, should be carefully evaluated prior to using SkinTE. Such conditions may prevent successful outcomes or lead to suboptimal results. Failure to ensure proper aseptic technique may result in contamination of the harvested skin, donor site, tissue product and/or wound bed, and could result in potential adverse events including local, regional, or systemic infection, failure of the graft to take upon deployment, failure of skin to heal and/or regenerate, deleterious effects on potential surrounding or adjacent reconstructions including infection, failure of adjacent grafted material to take and heal, the need for further surgical operations(s), and/or debridement or other serious injuries or death. Failure to follow instructions may lead to suboptimal outcomes, product failure and/or patient harm. Outcomes may vary. Risks also include those associated with skin grafting such as graft failure, infection, and/or effects on adjacent tissue or reconstructions.